Butabarbital will reduce the level or influence of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Result of coadministering a strong CYP3A4 inducer with fedratinib has not been studied. butabarbital will lower the level or impact of fosphenytoin by impacting hepatic enzyme CYP2C9/ten metabolism. https://immanuelp012bya1.azuria-wiki.com/user